Андреенко, Т. И.Солдатов, А. А.Головина, И. В.2024-08-232024-08-232009Андреенко Т. И., Солдатов А. А., Головина И. В. Адаптивная реорганизация метаболизма у двустворчатого моллюска Anadara inaequivalvis Bruguiere в условиях экспериментальной аноксии // Доповіді НАН України. 2009. № 7. С. 155-160.УДК: 594.1:577.121:612.22https://repository.marine-research.ru/handle/299011/14288Under experimental anoxia conditions, the processes of protein catabolism intensified in gills andfoot of the Black Sea bivalve mollusk Anadara inaequivalvis Bruguiere which resulted in a reduction of the protein content and a rise of free amino acids and urea levels in these tissues. Mainlylow-molecular peptides underwent hydrolysis. Decrease in the katepsin D activity and increase inthe activity ofγglutamyl transferase confirmed it. The anoxia was accompanied by the amplification of succinate thiokinase and fumarate reductase reactions controlled by aspartate and alaninetransaminases. These enzymes prevent the accumulation of toxic lactate in tissues and allow one to receive an additional ATP and GTP resource. The activity of lactate dehydrogenase reduced,whilst the malate dehydrogenase activity kept high. Metabolic processes in mollusk digestive gland at anoxia involved the production of amino acids, instead of their utilization.ru